NAD+ Infusion in Dublin: A Doctor's Guide to IV NAD Therapy

Nicotinamide adenine dinucleotide (NAD+) is a naturally occurring coenzyme found in every living cell. It is essential for many biological processes, including cellular energy production, DNA repair, metabolism and normal cellular function. A NAD+ infusion delivers it directly into the bloodstream.

At Dr. Torun's Clinic in Tallaght, Dublin, every NAD+ infusion is assessed and supervised by a doctor. This guide explains what the treatment involves, the evidence behind it, and how we keep it safe.

A NAD+ infusion is an intravenous (IV) therapy that delivers NAD+ directly into the bloodstream. NAD+ plays a critical role in converting nutrients into usable energy within the mitochondria, often described as the "powerhouses" of the cell. It also acts as a cofactor for enzymes involved in maintaining cellular health, regulating metabolism and supporting the body's response to oxidative stress.

NAD+ levels naturally decline with age, and can also be affected by illness, chronic stress and certain lifestyle factors. NAD+ infusions are commonly offered in wellness and integrative medicine settings to support energy metabolism, mental clarity, recovery and overall well-being. They have also been investigated as an adjunctive therapy in selected medical conditions, including substance use recovery and certain neurological disorders.

It is important to be honest about the evidence. Scientific support for many of the proposed wellness and anti-ageing benefits of NAD+ remains limited, and further high-quality clinical research is needed to establish its effectiveness and long-term safety.

Unlike iron or vitamin B12 therapy, there is no laboratory test that measures who "needs" a NAD+ infusion in routine clinical practice. Instead, baseline testing is used to identify any underlying conditions and to make sure the infusion is safe for you. Depending on your history, a clinician may consider:

• Complete blood count (CBC): to screen for anaemia or infection
• Comprehensive metabolic panel (CMP): kidney and liver function, and electrolytes
• Kidney function: creatinine and eGFR
• Liver function tests: AST, ALT, ALP and bilirubin
• Fasting glucose or HbA1c: to evaluate glucose metabolism
• Lipid profile: for cardiovascular risk
• Thyroid function (TSH, with Free T4 if needed): to assess causes of fatigue
• Vitamin B12 and folate: to identify deficiency
• Ferritin and iron studies: to evaluate iron status
• Vitamin D and magnesium: to check baseline levels
• Pregnancy test: when appropriate

Optional tests, depending on your symptoms, may include high-sensitivity CRP (inflammation), vitamin B1 (thiamine) and hormone testing (only when clinically indicated).

Reported benefits of NAD+ infusions include:

• Energy metabolism: increased energy, less fatigue and better exercise tolerance
• Cognitive function: mental clarity, concentration and reduced "brain fog"
• Cellular metabolism: support for mitochondrial function, cellular energy production and DNA repair pathways

Individual responses vary, and we will always set honest expectations before you start.

NAD+ infusions are generally well tolerated, but they can cause side effects. Common ones include warm flushing, chest tightness, nausea, abdominal discomfort, headache, fatigue during the infusion, lightheadedness and muscle cramps. These symptoms often improve when the infusion rate is slowed, which is why we give NAD+ slowly and adjust the pace to how you feel.

Less common effects include anxiety, palpitations, dizziness, vomiting, vein irritation (phlebitis) and injection-site pain. Rare but serious risks include allergic reactions, electrolyte disturbances, fainting and changes in heart rhythm. This is why the infusion is supervised throughout.

A NAD+ infusion may be considered for:

• Individuals with persistent fatigue, once common medical causes have been ruled out, such as anaemia, thyroid disorders, vitamin B12 or iron deficiency, sleep disorders (for example sleep apnoea), depression or anxiety, diabetes and chronic infections
• Adults with age-related decline in vitality: reduced energy, slower recovery after exercise, mild "brain fog" or a general decline in well-being
• People with metabolic disorders: obesity, prediabetes, type 2 diabetes, metabolic syndrome or non-alcoholic fatty liver disease
• Individuals with neurodegenerative conditions who may benefit, such as Parkinson's disease, Alzheimer's disease, multiple sclerosis or motor neurone disease (ALS)
• People in recovery from substance use disorders: some addiction programmes use NAD+ infusions during recovery from alcohol, opioid or stimulant use
• Athletes and active individuals: for recovery after intense training, reduced fatigue and improved endurance

Where fatigue is the main concern, the right first step is a proper assessment to rule out treatable causes, rather than starting with a drip.

We take a doctor-led, assessment-first approach. Before any NAD+ drip, we review your history and goals, arrange any bloods that are appropriate, and give the infusion slowly and comfortably under supervision.

Interested in a NAD+ infusion done properly and safely? Book a consultation or explore our full range of IV therapy services.

Frequently asked questions